When most people think of Botox, cosmetic wrinkle treatment comes to mind—softening lines on the forehead, crow’s feet around the eyes, and those deep frown lines between the eyebrows called the glabella. But beyond these popular uses, Botox also offers surprising mental health benefits, including helping ease symptoms of depression. Even better, it can help you feel more relaxed in your own skin—your authentic self.

How Botox Works Beyond Wrinkles

Botox is a neuromodulator that works by temporarily relaxing muscles, which smooths wrinkles caused by repeated facial expressions. The classic treatment areas are:

• Glabella (the area between the eyebrows, frown lines)
• Forehead lines
• Crow’s feet (lines around the eyes)

Treatment takes just minutes, with minimal discomfort and no downtime.

Treating the Glabella to Help Depression

Research shows that Botox injections in the glabella can actually help improve depression symptoms. The science is based on the "facial feedback hypothesis" — the idea that the muscles in our face send signals to our brain about our emotional state. When we frown, those signals can reinforce negative feelings.

By relaxing the muscles in the glabella, Botox reduces the ability to frown deeply, breaking the feedback loop that may perpetuate sadness or depression. Multiple clinical studies have demonstrated meaningful improvements in depression after injection in this area, often showing results within 2 to 6 weeks. This approach can be especially helpful for patients who have not found relief from traditional antidepressants.​

Feeling Like Your Authentic Self

Botox treatments in areas like the forehead and crow’s feet not only smooth wrinkles but also help your face appear more relaxed and natural. Many patients report feeling more like themselves after treatment, less weighed down by tension or worry lines that may not reflect how they feel inside. The subtle softening of expression can boost confidence and support emotional wellbeing.

When Will You See Results?

• Botox typically begins working within 1 to 3 days after treatment.
• Initial improvement is noticeable in about 2 to 4 days.
• Maximum results usually appear around 1 to 2 weeks.
• The mood-lifting benefits associated with glabellar treatment may take several weeks to fully manifest.​
• How Often Should You Get Treatments?

• The effects of Botox generally last about 3 to 4 months.
• Many patients schedule treatments every 3 to 4 months to maintain results and continued benefits.
• The exact frequency can vary depending on muscle strength, individual response, and desired outcomes.​ 

If you want to explore treatments that can support both your skin and spirit, Botox offers a unique, non-invasive option to consider. Schedule a consultation with Dr. Schneider at Pacific Crest Dermatology to see if this therapy may be right for you—helping you feel smoother on the outside and lighter on the inside.