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Dermatologist explaining why Neosporin can cause skin irritation and what to use instead for wound care

Why You Should Ditch Your Neosporin: A Dermatologist Explains

wound care Jul 28, 2025

It’s been in your medicine cabinet for years. You cut yourself, reach for the Neosporin, and move on. But what if we told you that this over-the-counter antibiotic ointment might be doing more harm than good?

At Pacific Crest Dermatology in Carson City, NV, we see a lot of patients with irritated, inflamed, or non-healing wounds—and one common culprit is Neosporin. Here's why dermatologists are moving away from recommending it—and what safer, more effective options you should be using instead.


1. Neosporin Can Cause Allergic Reactions

One of the biggest concerns with Neosporin is allergic contact dermatitis—a red, itchy rash that develops where the ointment is applied. This reaction is more common than you might think, especially with repeated use.

Neosporin contains neomycin, one of the most common topical allergens. It also includes polymyxin B and bacitracin, which can also irritate sensitive skin.

💡 Derm Tip: If your skin is getting more red, itchy, or inflamed after using Neosporin, stop using it and see a dermatologist. It might not be the cut that’s the problem—it might be the ointment.


2. Antibiotic Ointments Aren’t Always Necessary

Most minor cuts, scrapes, and abrasions don’t need a triple antibiotic. In fact, keeping the wound clean and moist is often enough to promote proper healing and reduce the risk of infection.

Overuse of topical antibiotics like Neosporin can also contribute to antibiotic resistance, which is a growing concern in both medicine and dermatology.


3. Better Options Exist for Wound Healing

Instead of reaching for Neosporin, try these dermatologist-approved alternatives:


4. When to See a Dermatologist

If a wound isn’t healing, looks infected, or you’ve developed a rash after using Neosporin or another topical product, it’s time to check in with a dermatologist.

At Pacific Crest Dermatology, we’re here to help you choose the right products to support your skin’s natural healing process—without causing allergic reactions or unnecessary side effects.


The Bottom Line

Neosporin has been a household staple for decades, but it’s not always the best choice. For most people, simple petroleum jelly and good wound care habits are all you need. If your skin is sensitive, you’ve had allergic reactions, or you want personalized recommendations, book a visit with a board-certified dermatologist.

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